The only known example of Matteo Pagano's Map of the 1541 Conquest of Tunis, engraved in Venice by the master engraver Matteo Pagano.
The 1541 Algiers expedition occurred when Charles V of the Holy Roman Empire attempted to lead an amphibious attack against the Ottoman Empire's stronghold of Algiers, in modern Algeria. Inadequate planning, particularly against unfavourable weather, led to the failure of the expedition.
Algiers had been under the control of the Ottoman Emperor Suleiman the Magnificent since its capture in 1529 by Barbarossa. Barbarossa had left Algiers in 1535 to be named High Admiral of the Ottoman Empire in Constantinople, and was replaced as governor by Hassan Agha, a eunuch and Sardinian renegade. Hassan had in his service the well-known Ottoman naval commanders Dragut, Sālih Reïs, and Sinān Pasha.
Charles V made considerable preparations for the expedition, wishing to obtain revenge for the recent siege of Buda. However the Spanish and Genoese fleets were severely damaged by a storm, forcing him to abandon the venture. The Expedition began in late September 1541, delayed by troubles in Germany and Flanders. The fleet was assembled in the Bay of Palma, at Majorca. It had more than 500 sails and 24,000 soldiers. After enduring difficult weather, the fleet only arrived off the coast of Algiers on October 19. The most distinguished Spanish commanders accompanied Charles V on this expedition, including Hernán Cortés, the conqueror of Mexico, though he was never invited to the War Council.
Charles established his headquarters on a land promontory surrounded by German troops. German, Spanish, and Italian troops, accompanied by 150 Knights of Malta, began to land while repelling Algerine opposition, soon surrounding the city, except for the northern part. The fate of the city seemed to be sealed, however the following day the weather became severe with heavy rains. Many galleys lost their anchors and 15 were wrecked onshore. Another 33 carracks sank, while many more were dispersed. As more troops were attempting to land, the Algerines started to make sorties, slaughtering the newly arrived. Charles V was surrounded, and was only saved by the resistance of the Knights of Malta.
Andrea Doria managed to find a safer harbor for the remainder of the fleet at Cape Matifu, 5 miles east of Algiers. He enjoined Charles V to abandon his position and join him in Matifu, which Charles V did with great difficulty. From there, still oppressed by the weather, the remaining troops sailed to Bougie, still a Spanish harbor at that time. Charles abandoned his army and sailed home.